How ViziLite Plus Works

ViziLite Plus with TBlue is an oral lesion identification and marking system that is used as an adjunct to the conventional head and neck examination. It is comprised of a chemiluminescent light source (ViziLite) to improve the identification of lesions and a blue phenothiazine dye to mark those lesions identified by ViziLite. ViziLitePlus with TBlue is designed to be used in a patient population at increased risk for oral cancer.

Lumenoscopy^{TM -}  Examination of the Oral Cavity with ViziLite

In clinical trials involving 13,000 female patients, abnormal squamous epithelium in the cervical complex appears distinctly white after washing the cervix with a dilute acetic acid solution and viewed under chemiluminescent light (Speculite®).  Similarly, examination of the oral cavity under chemiluminescent light (ViziLite) after rinsing with a dilute acetic acid solution, abnormal squamous epithelium tissue will appear distinctly white. Lumenoscopy^TM has demonstrated in numerous studies to improve the ability to visualize mucosal lesions and initially identify clinically suspicious lesions. 

ViziLite Lumenoscopy^TM

TBlue^® Oral Lesion Marking System

TBlue is a patented, pharmaceutical-grade toluidine blue-based metachromatic dye.  It is used to further evaluate and closely monitor changes in ViziLite-identified lesions.  It has been proposed that living cells will differentially accumulate toluidine blue based on parameters related to metabolic activity.  TBlue , packaged in an easy to use 3-swab system, provides the deep blue staining that allows ViziLite-identified lesions to be seen clearly under normal light. 

For additional information, download the ViziLite Plus with TBlue package insert.